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AGC group inhibitors

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Inhibitors of protein kinases of the AGC family

AGC group inhibitors - The term...

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Subcategories

  • PKA inhibitors

    Selective cAMP-dependent protein kinase (PKA) inhibitors

    PKA inhibitors - PKA / cAMP dependent protein kinase is a member of the serine-threonine protein kinase superfamily (AGC group) and the main intracellular target for the second messenger cAMP in mammalian cells. The kinase is involved in the control of a variety of cellular processes and serves as molecular target for cancer therapy and research. Proteinkinase.de offers potent inhibitors selective against cAMP-dependent protein kinase PKA.

    PKA Inhibitors - Inhibitors of cAMP dependent protein kinase

  • PKG inhibitors

    Selective cGMP dependent kinase (PKG) inhibitors

    PKG inhibitors - Cyclic GMP-dependent protein kinases (PKG / cGMP dependent protein kinase) are serine/threonine kinases and central mediators of the NO-cGMP signaling pathway. The category of Proteinkinase.de includes specific and potent PKG inhibitor molecules.

    PKG Inhibitors - Inhibitors of cGMP dependent protein kinase

  • PKC inhibitors

    Selective protein kinase C (PKC) family inhibitors

    PKC Inhibitors - Inhibitors of protein kinase C - Protein kinase C (PKC) belongs to a family of serine/threonine protein kinases. PKC family proteins are subdivided into three subfamilies based on their domain structure and cofactor requirements and regulate diverse cellular processes and have been proven to be attractive drug targets. This category includes specific small molecule inhibitor of PKC family enzymes.

    PKC Inhibitors - Inhibitors of protein kinase C

  • PKB inhibitors

    Selective protein kinase B (PKB) / Akt family inhibitors

    PKB / Akt kinase Inhibitors - The PKB Akt kinase family is comprised of three highly homologous isoforms: Akt1 (PKBα), Akt2 (PKBβ) and Akt3 (PKBγ). The PKB Akt kinase family is activated downstream of PI3-kinase and is involved in numerous cellular processes as cell growth, survival and proliferation. Furthermore, especially Akt2 is an important signaling molecule in the Insulin signaling pathway. The small molecule inhibitors of this category are specific and selective PKB Akt inhibitors.

    PKB / Akt kinase Inhibitors


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