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Coelenterazine, 1 mg  

Coelenterazine, 1 mg

Coelenterazine, synthetic, high purity bioluminescent substrate

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165,00 €

Coelenterazine or coelenterate luciferin is the substrate for a number of bioluminescent reactions, including those from the marine species Renilla, Aequorea and Watesenia. In some of these reactions it is utilized as a simple substrate being catalytically turned over in the bioluminescent reaction, while in others, such as in the photoprotein systems of Mneiopsis, it is incorporated as part of the photoprotein.

Coelenterazine, 1, 5mg:    order-no. COE-001, COE-005

Chemical Name:  2-[(4-Hydroxyphenyl)methyl]-6-(4-hydroxyphenyl)-8-(phenylmethyl)-imidazo [1,2-a] pyrazin-3-(7H)-one
CAS – No.:             55779-48-1
Formula:               C26H21N3O3
Molecular Weight: 423.5
Storage:   storage -20°C (upon arrival), Protect from Light. Keep under Inert Gas. Keep Calcium free when stored in solution.
Appearance:        Brown Solid
Solubility:             Slightly Soluble in Methanol or Ethanol. Avoid DMSO

Product Citations:

Breit A, Wolff K, Kalwa H, Jarry H, Büch T, Gudermann T. (2006) "The natural inverse agonist agouti-related protein induces arrestin-mediated endocytosis of melanocortin-3 and -4 receptors." J Biol Chem. 281(49):37447-56.

Hofmann T, Schäfer S, Linseisen M, Sytik L, Gudermann T, Chubanov V. (2014) "Activation of TRPM7 channels by small molecules under physiological conditions." Pflugers Arch. 466(12):2177-89.

Stenger B, Zehfuss F, Mückter H, Schmidt A, Balszuweit F, Schäfer E, Büch T, Gudermann T, Thiermann H, Steinritz D. (2015) "Activation of the chemosensing transient receptor potential channel A1 (TRPA1) by alkylating agents."Arch Toxicol. 2015 Sep;89(9):1631-43.

Schäfer S, Ferioli S, Hofmann T, Zierler S, Gudermann T., Chubanov V. (2016) "Mibefradil represents a new class of benzimidazole TRPM7 channel agonists" Pflugers Arch.468(4):623-34.

PLEASE NOTE: This product is designed for research purposes and can only be delivered to academic and business customers.  

Product Citations of Biaffins Coelenterazine:

Anna Rössig, Kerstin Hill, Wolfgang Nörenberg, Sebastian Weidenbach, Susanna Zierler, Michael Schaefer, Thomas Gudermann, Vladimir Chubanov (2022) "Pharmacological agents selectively acting on the channel moieties of TRPM6 and TRPM7" Cell Calcium, 106:102640. doi: 10.1016/j.ceca.2022.102640.