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Recombinant human CEACAM1 /CD66a /BGP1 Protein, 1mg  

Recombinant human CEACAM1 /CD66a /BGP1 Protein, 1mg

Recombinant Human CEACAM1 /CD66a /BGP1 Protein (rhCEACAM1 /CD66a) Gln 35 - Gly 428 was produced in human 293 cells (HEK293), His Tag

Synonym recombinant, human, protein CEACAM1, CD66a, BGP, BGP1, BGPI

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Availability: within 7 days

1 500,00 €

Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), also known as Biliary glycoprotein 1 (BGP1), CD66a, which belongs to the immunoglobulin superfamily or CEA family. CEACAM1 /CD66a contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CEACAM1 /CD66a was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 / BGP-1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.

Recombinant Human CEACAM1 /CD66a /BGP1 Protein (rhCEACAM1 /CD66a) Gln 35 - Gly 428 (Accession # AAH14473) was produced in human 293 cells (HEK293).

Molecular Characterization
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 44.2 kDa. The protein migrates as 57-100 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.

Less than 1.0 EU per μg of the rhCEACAM1 /CD66a by the LAL method.

>92% purity as determined by SDS-PAGE.

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization.

See Certificate of Analysis for details of reconstitution instruction and specific concentration.

Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at:
In lyophilized state for 1 year (4°C-8°C); After reconstitution under sterile conditions for 1 month (4°C-8°C) or 3 months (-20°C to -70°C).

Immobilized Human CEACAM-1, His Tag (Cat. No. CE1-H5220) at 10 μg/mL (100 μL/well) can bind Biotinylated Human CEACAM-8, His,Avitag (Cat. No. CE8-H82E9) with a linear range of 0.039-1.25 μg/mL (QC tested).


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