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Recombinant Human CD147 Protein, Fc Tag, 1mg  

Recombinant Human CD147 Protein, Fc Tag, 1mg

Recombinant Human CD147 / EMMPRIN / Basigin Protein (Ala 22 - His 205), produced in human 293 cells (HEK293), Fc Tag

Recombinant Human Protein, Basigin, BSG, 5F7, CD147, EMMPRIN, M6, OK, TCSF

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1 600,00 €

CD147, also known as Basigin (BSG), or extracellular matrix metalloproteinase inducer (EMMPRIN). The human basigin protein contains 269 amino acids that form two heavily glycosylated C2 type immunoglobulin-like domains at the N-terminal extracellular portion. A second form of basigin has also been characterized that contains one additional immunoglobulin-like domain in its extracellular portion. As members of the immunoglobulin superfamily play fundamental roles in intercellular recognition involved in various immunologic phenomena, differentiation, and development, basigin is thought also to play a role in intercellular recognition and regulate several distinct functions, such as spermatogenesis, expression of the monocarboxylate transporter and the responsiveness of lymphocytes. Basigin is a type I integral membrane receptor that has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins.

Recombinant Human CD147 /EMMPRIN /Basigin Protein, With C-Fc Tag (rhCD147-Fc) Ala 22 - His 205 (Accession # NP_940991.1) was produced in human 293 cells (HEK293)

Molecular Characterization
rhCD147-Fc, fused with Fc fragment of human IgG1 at the C-terminus, has a calculated MW of 46.3 kDa. The predicted N-terminus is Ala 22. DTT-reduced Protein migrates as 50-65 kDa due to glycosylation.

Less than 1.0 EU per μg of the rhCD147-Fc by the LAL method.

>95% as determined by SDS-PAGE.

Lyophilized from 0.22 μm filtered solution in 50 mM tris, 100 mM glycine, pH7.0. Normally Mannitol or Trehalose are added as protectants before lyophilization.

See Certificate of Analysis for details of reconstitution instruction and specific concentration.

Avoid repeated freeze-thaw cycles.
No activity loss was observed after storage at:
In lyophilized state for 1 year (4°C-8°C); After reconstitution under sterile conditions for 1 month (4°C-8°C) or 3 months (-20°C to -70°C).


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