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Recombinant Human CD69 / CLEC2C Protein, His tag, 1mg  

Recombinant Human CD69 / CLEC2C Protein, His tag, 1mg

Recombinant Human CD69 / CLEC2C Protein (Ser 62 - Lys 199), produced in human 293 cells (HEK293), His tag

Recombinant human protein, CD69, CLEC2C, AIM, BL-AC/P26, EA1, GP32/28, MLR-3

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Availability: within 7 days

1 600,00 €

Early activation antigen CD69 is also known as C-type lectin domain family 2 member C (CLEC2C), Activation inducer molecule (AIM), Early T-cell activation antigen p60, Leukocyte surface antigen Leu-23. CD69 contains one C-type lectin domain. CD69 / CLEC2C is expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets. CD69 is induced by antigens, mitogens or activators of PKC on the surface of T and B-lymphocytes and by interaction of IL-2 with the p75 IL-2R on the surface of NK cells. CD69 / CLEC2C involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.

Recombinant Human CD69 /CLEC2C Protein (rhCD69) Ser 62 - Lys 199 (Accession # AAH07037) was produced in human 293 cells (HEK293).

Molecular Characterization
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 16.8 kDa. The protein migrates as 20-26 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.

Less than 1.0 EU per μg of the rhCD69 by the LAL method.

>95% as determined by SDS-PAGE.

Human CD69, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization.

See Certificate of Analysis for details of reconstitution instruction and specific concentration.

Avoid repeated freeze-thaw cycles.
No activity loss was observed after storage at:
In lyophilized state for 1 year (4°C-8°C); After reconstitution under sterile conditions for 1 month (4°C-8°C) or 3 months (-20°C to -70°C).


(1) Natarajan K., et al., 2000, Biochemistry 39:14779-14786.
(2) Llera A.S., et al., 2001, J. Biol. Chem. 276:7312-7319.
(3) Vanek O., et al., 2008, FEBS J. 275:5589-5606.