kinases protein kinase inhibitors signaling activators kinase substrates antibodies bioluminescence assays
Recombinant Human CD44 Protein, Fc Tag (HPLC-verified), 4 x 250 µg  

Recombinant Human CD44 Protein, Fc Tag (HPLC-verified), 4 x 250 µg

Recombinant Human CD44 Protein (Gln 21 - Pro 220), produced in human 293 cells (HEK293), Fc Tag, HPLC-verified

Recombinant human protein, CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, Epican

More details


Availability: within 7 days

1 650,00 €

CD44 antigen is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration. CD44 is expressed in a large number of mammalian cell types. CD44 is a receptor for hyaluronic acid and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). CD44 function is controlled by its posttranslational modifications. One critical modification involves discrete sialofucosylations rendering the selectin-binding glycoform of CD44 called HCELL (for Hematopoietic Cell E-selectin/L-selectin Ligand). CD44 participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms.

Recombinant Human CD44, Fc Tag (HPLC-verified) (PG1-H5255) is expressed from human 293 cells (HEK293). It contains AA Gln 21 - Pro 220 (Accession # AAH04372).
Predicted N-terminus: Gln 21

Molecular Characterization
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 48.7 kDa. The protein migrates as 55-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Less than 1.0 EU per μg by the LAL method.

>95% as determined by SDS-PAGE.
>90% as determined by SEC-HPLC.

Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

See Certificate of Analysis for reconstitution instructions and specific concentrations.

Avoid repeated freeze-thaw cycles.
No activity loss was observed after storage at:
In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C).

Please refer to product data sheet.


(1) Goodison S., et al., 1999, MP, Mol. Pathol. 52 (4): 189–96.
(2) Hanley WD., et al., 2005, Cancer Res. 65 (13): 5812–7.
(3) Burdick MM., et al., 2006, J. Biol. Chem. 281 (20): 13899–905.
(4) Thomas SN., et al., 2008, J Biol Chem 283 (23): 15647–55.