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Recombinant human protein kinase TAOK3, 10 µg  

Recombinant human protein kinase TAOK3, 10 µg

Recombinant human Thousand and one amino acid protein 3, TAOK3, full lenght, amino acids M1-R898, untagged, expressed in Sf9 insect cells, active enzyme

Alternate names: Kinase from chicken homolog A, Dendritic cell-derived protein kinase, Jun kinase-inhibitory kinase, Cutaneous T-cell lymphoma-associated antigen HD-CL-09, Thousand and one amino acid protein 3, DPK, JIK

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PK-TAOK3-A010

Availability: within 14 days

465,00 €

Background: Thousand and one amino acid (TAO) kinases are Ste20p-related MAP kinase kinase kinases (MAP3Ks). The Tao kinase subfamily has three members in mammals: TAOK1 (also known as MAP3K16, PSK2 or MARKK); TAOK2 (MAP3K17 or PSK1) and TAOK3 (MAP3K18, JIK or DPK)). TAOs are important regulators of genotoxic stress response and regulate e.g. p38 via their ability to phosphorylate and activate the MAPK kinases MEK3 and 6. Furthermore, TAOs have been implicated in regulation of cytoskeleton stability, G protein-coupled receptor signaling to p38, and cell survival.

Recombinant Human TAOK3 (Thousand and one amino acid protein 3), amino acids M1-R898, recombinant and active protein, untagged, expressed in Sf9 insect cells

Theoretical MW : 106.015 kDa (fusion proteins)
Expression system: Baculovirus infected Sf9 cells
Purification: GST-Affinity Chromatography
Storage buffer: 50 mM HEPES pH 7.5, 100 mM NaCl, 5 mM DTT, 20% glycerol
Protein concentration: 0.124 mg/ml (Bradford method using BSA as standard protein)
Method for determination of Km value & specific activity: Filter binding assay MSPH membrane
Specific activity : 1,000 pmol/mg min

Entrez Gene ID 51347 
UniProtKB Q9H2K8

Ordering information: shipped on dry ice