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CK2 protein kinase inhibitor TTP 22, 10 mg  

CK2 protein kinase inhibitor TTP 22, 10 mg

3-(5-p-tolylthieno[2,3-d]pyrimidin-4-ylthio)propanoic acid

TTP 22 is a potent casein kinase 2 (CK2) inhibitor

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PKI-TTP22-010

Availability: within 3 days

156,00 €

Background: TTP 22 is a potent and ATP-competitive casein kinase 2 (CK2) inhibitor (IC50 = 0.1 μM, Ki = 40 nM). Displays selectivity for CK2 over JNK3, ROCK1 and MET (no inhibitory effects at 10 μM).

Chemical formula: C16H14N2O2S2
Molecular weight: 330.42 g/mol
Purity: 99%
Appearance: White Solid
Solubility: Soluble in 0.1N NaOH(aq) and DMSO
CAS Number: 329907-28-0

Manufacturer:  Axon Medchem BV

PLEASE NOTE: This product is designed for research purposes and can only be delivered to academic and business customers. 

References

AG Golub et al. Synthesis and biological evaluation of substituted (thieno[2,3-d]pyrimidin-4-ylthio)carboxylic acids as inhibitors of human protein kinase CK2. Eur. J. Med. Chem. 2011, 46(3), 870-6.

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