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JAK2 protein kinase inhibitor 13, 5 mg  

JAK2 protein kinase inhibitor 13, 5 mg

4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide

Synonyms: Sulfonamide 13
JAK2 inhibitor 13 is a potent and selective Janus Kinase 2 (JAK2) inhibitor

More details

PKI-JAK2-005

Availability: within 3 days

156,00 €

Background: JAK2 inhibitor 13 is a potent and selective Janus Kinase 2 (JAK2) inhibitor; inhibits the activity of both the wild-type JAK2 and the V617F mutant (IC50 = 78 and 206 nM, respectively), with >35-fold selectivity versus JAK3 (IC50 = 2.93 µM).

Chemical formula: C17H20N4O2S
Molecular weight: 344.43 g/mol
Purity: 99 %
Appearance: White solid
Solubility: Soluble in DMSO
CAS Number: 1110502-30-1

Manufacturer:  Axon Medchem BV

PLEASE NOTE: This product is designed for research purposes and can only be delivered to academic and business customers.  

References

S Antonysamy et al. Fragment-based discovery of JAK-2 inhibitors. Bioorg. Med. Chem. Lett. 2009, 19(1), 279-282.