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JNK protein kinase inhibitor CC 401, 5 mg  

JNK protein kinase inhibitor CC 401, 5 mg

3-(3-(2-(piperidin-1-yl)ethoxy)phenyl)-5-(1H-1,2,4-triazol-5-yl)-1H-indazole

CC 401 is a second generation ATP-competitive c-Jun N terminal kinase (JNK) inhibitor with potential antineoplastic activity

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PKI-CC401-005

Availability: within 3 days

169,00 €

Background: CC 401 is a second generation ATP-competitive c-Jun N terminal kinase (JNK) inhibitor with potential antineoplastic activity.

Chemical formula: C22H24N6O
Molecular weight: 388.47 g/mol
Purity: 99 %
Appearance: Off-white crystals
Solubility: Soluble in DMSO and Ethanol
CAS Number: 395104-30-0

Manufacturer:  Axon Medchem BV

PLEASE NOTE: This product is designed for research purposes and can only be delivered to academic and business customers.  

References

T Uehara et al. JNK mediates hepatic ischemia reperfusion injury. J. Hepatol. 2005, 42(6), 850-859.
 
FY Ma et al. A pathogenic role for c-Jun amino-terminal kinase signaling in renal fibrosis and tubular cell apoptosis. J. Am. Soc. Nephrol. 2007, 18(2), 472-484.