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AKT and PDK1 protein kinase inhibitor PHT 427, 10 mg  

AKT and PDK1 protein kinase inhibitor PHT 427, 10 mg

4-dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide

PHT 427 is an inhibitor of AKT and phosphoinositide-dependent protein kinase 1 (PDPK1 or PDK1)

More details

PKI-PHT427-010

Availability: within 3 days

127,50 €

Background: PHT 427 is an inhibitor of AKT and phosphoinositide-dependent protein kinase 1 (PDPK1 or PDK1). PH 427 binds to the pleckstrin homology (PH) domain of Akt and PDPK1 signaling with significant in vivo antitumor activity and minimal toxicity.

Chemical formula: C20H31N3O2S2
Molecular weight: 409.61 g/mol
Purity: 99 %
Appearance: White solid
Solubility: Soluble in DMSO
CAS Number: 1191951-57-1

Manufacturer:  Axon Medchem BV

PLEASE NOTE: This product is designed for research purposes and can only be delivered to academic and business customers.  

References

EJ Meuillet et al. Molecular Pharmacology and Antitumor Activity of PHT-427, a Novel Akt/Phosphatidylinositide-Dependent Protein Kinase 1 Pleckstrin Homology Domain Inhibitor. Mol. Cancer Ther. 2010, 9, 706.

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