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TKL

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Recombinant protein kinases of the tyrosine kinase like group (TKL)

The Tyr kinase-like (TKL) group is closely related to the Tyrosine kinase group (TK) although the kinase group comprises predominantly serine/threonine kinases. Prominent mebers are the the Raf family kinases, acting as important components of the MAP kinase pathway, and TGF beta receptors involved in in many cellular processes such as cell growth, cell differentiation and apoptosis.