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cAMP-dependent protein kinase, PKA

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cAMP-dependent protein kinase (PKA)

cAMP-dependent protein kinase - PKA is an ubiquitous serine-theonine protein kinase present in a variety of tissues. The intracellular cAMP level regulates cellular responses by altering the interaction between the catatytic C and regulatory R subunits of PKA. The inactive PKA holoenzyme is activated when cAMP binds to the regulatory subunits which induces the release of two active catalytic subunits.

cAMP-dependent protein kinase - PKA - catalytic and regulatory subunits - holo enzyme