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ActiveMax® Recombinant Human IFN-gamma protein / IFNG, premium grade, 100 µg  

ActiveMax® Recombinant Human IFN-gamma protein / IFNG, premium grade, 100 µg

ActiveMax® Recombinant Human IFN-gamma protein / IFNG, Gln 24 - Gln 166, produced in human 293 cells (HEK293), Tag free, premium grade

Synonym: Recombinant Human Protein, Interferon-gamma, Interferon-γ

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Availability: within 7 days

195,00 €

Interferon-gamma (IFN-γ/IFNG) is a dimerized soluble cytokine that is the only member of the type II class of interferon. This interferon was originally called macrophage-activating factor, a term now used to describe a larger family of proteins to which IFN-γ belongs. IFN-gamma has been used in a wide variety of clinical indications. Interferon-gamma (IFNgamma) is a central regulator of the immune response and signals via the Janus Activated Kinase (JAK)-Signal Transducer and Activator of Transcription (STAT) pathway. Interferon gamma has broader roles in activation of innate and adaptive immune responses to viruses and tumors, in part through upregulating transcription of genes involved in cell cycle regulation, apoptosis, and antigen processing/presentation. Despite this, rodent and human trophoblast cells show dampened responses to IFNG that reflect the resistance of these cells to IFNG-mediated activation of major histocompatibility complex (MHC) class II transplantation antigen expression.

ActiveMax® Recombinant Human IFN-gamma protein / IFNG,premium grade(IFG-H4211) is expressed from human 293 cells (HEK293). It contains AA Gln 24 - Gln 166 (Accession # AAH70256).
Predicted N-terminus: Gln 24
It is produced under our rigorous quality control system that incorporates a comprehensive set of tests including sterility and endotoxin tests. Product performance is carefully validated and tested for compatibility for cell culture use or any other applications in the early preclinical stage. When ready to transition into later clinical phases, we also offer a custom GMP protein service that tailors to your needs. We will work with you to customize and develop a GMP-grade product in accordance with your requests that also meets the requirements for raw and ancillary materials use in cell manufacturing of cell-based therapies.

Molecular Characterization
This protein carries no "tag".
The protein has a calculated MW of 16.8 kDa. The protein migrates as 19-25 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.

Less than 0.1 EU per μg by the LAL method.

The sterility testing was performed by membrane filtration method.


>90% as determined by SDS-PAGE.

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.

Please refer to product data sheet.

Clinical and Translational Updates

(1) "PTPN2 is a Critical Regulator of Ileal Paneth Cell Viability and Function in Mice"
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(3) "TLR9 agonist CpG ODN 2395 promotes the immune response against Leishmania donovani in obesity and undernutrition mice"
He, Huang, Liao et al
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Showing 1-3 of 91614 papers.