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The synthetic peptide RSRHSSYPAGT can be used as a substrate for PIM kinase in in vitro kinase assays.
PIM substrate peptide: PEP-PIM-001
Amino acid sequence: RSRHSSYPAGT
Molecular Weight: 1218.3 g/mol
Shipment conditions: Room temperature
Long Term Storage: -20°C (AVOID FREEZE/THAW CYCLES)
Purity: 90-95% (HPLC)
Appearance: Lyophilized powder
Handling: Reconstitution of 1 mg in 2 ml water dest. results in a 400 µM solution used in the PIM activity assay.
Bullock AN, Debreczeni J, Amos AL, Knapp S, Turk BE. (2005), „Structure and substrate specificity of the Pim-1 kinase. “J Biol Chem. 280(50):41675-82.
Magnuson NS, Wang Z, Ding G, Reeves R. (2010) „Why target PIM1 for cancer diagnosis and treatment?”. Future Oncol. 6(9):1461-78.
Peng C, Knebel A, Morrice NA, Li X, Barringer K, Li J, Jakes S, Werneburg B, Wang L. (2007) "Pim kinase substrate identification and specificity." J Biochem. 141(3) 353-62.
PLEASE NOTE: This product is designed for research purposes and can only be delivered to academic and business customers.
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