DYRK family substrate, 1 mg

The synthetic peptide KKISGRLSPIMTEQ can be used as a substrate for DYRK family protein kinases in in vitro kinase assays. The peptide corresponds to residues 324-334 of transcription factor FKHR with two lysine residues added at the N-terminus to facilitate binding to phosphocellulose paper. Purity: 90-95% (HPLC), Molecular weight: 1588 g/mol. Form: solid.

Product specific literature references:

Woods YL, Rena G, Cohen P et al. (2001) "The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site" Biochem J. 355(Pt 3):597-607

PLEASE NOTE: This product is designed for research purposes and can only be delivered to academic and business customers.