kinases protein kinase inhibitors signaling activators kinase substrates antibodies bioluminescence assays
Recombinant human CEACAM6 /CD66c Protein, 100µg  

Recombinant human CEACAM6 /CD66c Protein, 100µg

Recombinant Human CEACAM6 /CD66c Protein (rhCEACAM6) Lys35-Gly320 was produced in human 293 cells (HEK293) His Tag.

Synonym: recombinant, human, protein CEACAM6,CD66c,CEAL,NCA 

More details


Availability: within 7 days

312,00 €

Carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (CEACAM6) also known as CD66c (Cluster of Differentiation 66c), CEAL, NCA, and is one of seven human CEACAM family members within the immunoglobulin superfamily. In humans, CEACAMs include type I transmembrane proteins (CEACAM1, CEACAM3, and CEACAM4) and GPI-linked molecules (CEACAM5 through CEACAM8). There is no human CEACAM2. CEACAM 6 contains one N-terminal V-type Ig-like domain (N domain), followed by two C2-type Ig-like domains. It shows considerable glycosylation, including (sialyl) LewisX, which mediates binding to E-selectin, galectins and some bacterial fimbrae. CEACAM-6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression. [1-5]

Recombinant Human CEACAM6 /CD66c Protein (rhCEACAM6) Lys35-Gly320 (Accession # NP_002474.3)was produced in human 293 cells (HEK293).

Molecular Characterization
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 32.0 kDa. The protein migrates as 45-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Less than 1.0 EU per μg of the rhCEACAM6 by the LAL method.

>95% as determined by SDS-PAGE.

Refer to data sheet

See Certificate of Analysis for details of reconstitution instruction and specific concentration.

Avoid repeated freeze-thaw cycles.
No activity loss was observed after storage at:
In lyophilized state for 1 year (4°C-8°C); After reconstitution under sterile conditions for 1 month (4°C-8°C) or 3 months (-20°C to -70°C).

Immobilized Human CEACAM-6, His Tag (Cat. No. CE6-H5223) at 10 μg/mL (100 μL/well) can bind Biotinylated Human CEACAM-8, His,Avitag (Cat. No. CE8-H82E9) with a linear range of 0.02-0.313 μg/mL (QC tested).


(1) Beauchemin, N. et al., 1999, Exp. Cell Res. 252:243.
(2) Skubitz, K.M. et al., 1999, J. Biol. Regul. Homeost. Agents 13:244.
(3) Tawaragi, Y. et al.,1988, Biochem. Biophys. Res. Comm. 150:89.
(4) Scholzel, S. et al., 2000, Am. J. Pathol. 156: 595-605.
(5) Duxbury, M.S. et al., 2004, J. Biol. Chem. 279: 23176-23182.