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Recombinant human CD27 / TNFRSF7 Protein, human Fc Tag, 200µg  

Recombinant human CD27 / TNFRSF7 Protein, human Fc Tag, 200µg

Recombinant Human CD27 /TNFRSF7 Protein, With C-Fc Tag (rhCD27 Fc Chimera) Thr 21 - Ile 192 was produced in human 293 cells (HEK293) (HPLC verified).

Synonym: recombinant human protein CD27,TNFRSF7,S152,T14,Tp55

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Availability: within 7 days

324,00 €

CD Antigen CD27 also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.

Recombinant Human CD27 /TNFRSF7 Protein, Fc Tag (CD7-H5254) is expressed from human 293 cells (HEK293). It contains AA Thr 21 - Ile 192 (Accession # NP_001233).
Predicted N-terminus: Thr 21

Molecular Characterization
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 45.9 kDa. The protein migrates as 53-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Less than 1.0 EU per μg of the rhCD27 Fc Chimera by the LAL method.

>95% as determined by SDS-PAGE.
>85% as determined by SEC-HPLC.

Lyophilized from 0.22 μm filtered solution in 50 mM tris, 100 mM glycine, pH7.0. Normally Mannitol or Trehalose are added as protectants before lyophilization.

Please refer to product data sheet.

See Certificate of Analysis for details of reconstitution instruction and specific concentration.

Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at:
In lyophilized state for 1 year (4°C-8°C); After reconstitution under sterile conditions for 1 month (4°C-8°C) or 3 months (-20°C to -70°C).


(1) Zhang Z., et al., 2004, Protein Sci. 13:2819-2824.
(2) Gravestein L.A., et al., 1998, Eur. J. Immunol. 28:2208-2216.
(3) Prasad K.V.S., et al., 1997, Proc. Natl. Acad. Sci. U.S.A. 94:6346-6351.