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5' AMP-activated protein kinase / AMPK or 5' adenosine monophosphate-activated protein kinase is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. 5'-AMP-activated protein kinase catalytic subunit alpha-1 is an enzyme that in humans is encoded by the PRKAA1 gene.
Human AMPK-alpha1, Amino acids M1-L310 , N-terminally fused to GST-Thrombin cleavage site
Theoretical MW: 63.260 kDa (fusion protein)
Expression system: E.coli
Storage buffer: 50 mM Tris-HCl, 150 mM NaCl, 1 mM DTT, 0.05 % Brij, 10% glycerol, pH 7.5
Protein concentration: 0.29 mg/ml (Bradford method using BSA as standard protein)
Purity: 60%
Entrez Gene ID: 5562
UniProtKB: Q13131
Ordering informations: shipped on dry ice
Hardie DG (2007) "Annu Rev Pharmacol Toxicol." AMP-activated protein kinase as a drug target" 47:185-210.
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