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The synthetic peptide KKKVSRSGLYRSPSMPENLNRPR can be used as a substrate for checkpoint kinases CHK1 and CHK2 in in vitro kinase assays. Its sequence is derived from cdc25C.
Purity: 90-95% (HPLC)
Molecular weight: 2701 g/mol
Form: solid
PLEASE NOTE: This product is designed for research purposes and can only be delivered to academic and business customers.
O\'Neill T, Giarratani L et al. (2002) Determination of substrate motifs for human Chk1 and hCds1/Chk2 by the oriented peptide library approach. J Biol Chem 277:16102-15.
Koledova Z1, Kafkova LR, Krämer A, Divoky V. (2010) "DNA damage-induced degradation of Cdc25A does not lead to inhibition of Cdk2 activity in mouse embryonic stem cells." Stem Cells. 28(3):450-61.
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