Fc gamma RIIA / CD32

Fc gamma RIIA / CD32 - Low affinity immunoglobulin gamma Fc region receptor II

There are three genes for human Fcγ RII /CD32 (A, B, and C) and one for mouse Fcγ RII B (CD32B). CD32 is a low affinity receptor for IgG. The activating isoform, CD32A, is expressed on monocytes, neutrophils, platelets and dendritic cells. CD32A delivers an activating signal upon ligand binding, and results in the initiation of inflammatory responses including cytolysis, phagocytosis, degranulation and cytokine production. The responses can be modulated by signals from the coexpressed inhibitory receptors such as CD32B, and the strength of the signal is dependent on the ratio of expression of the activating and inhibitory receptors.

Human Fc gamma RIIA / CD32a (H167) Protein
Human Fc gamma RIIA / CD32a (R167) Protein
Rat Fc gamma RIIA / CD32a Protein
Cynomolgus Fc gamma RIIA / CD32a Protein
Rhesus macaque Fc gamma RIIA / CD32a Protein

Mouse Fc gamma RIIB / CD32b Protein
Rat Fc gamma RIIB / CD32b Protein
Cynomolgus Fc gamma RIIB / CD32b Protein
Human Fc gamma RIIB/C (CD32b/c) Protein