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Recombinant human EGFR /ErbB1 Protein, Fc Tag, 100µg  

Recombinant human EGFR /ErbB1 Protein, Fc Tag, 100µg

Recombinant Human EGFR /ErbB1 Protein, AA Leu 25 - Ser 645, produced in human 293 cells (HEK293), Fc Tag (MALS verified)

Synonym: recombinant human protein, EGFR, ERBB, ERBB1, HER1, PIG61, mENA

More details


Availability: within 7 days

270,00 €

The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands.[1] The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.[2]

Recombinant Human EGF R, Fc Tag (EGR-H5252) is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Ser 645 (Accession # P00533-1).
Predicted N-terminus: Leu 25

Molecular Characterization
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 94.7 kDa. The protein migrates as 110-140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Less than 1.0 EU per µg of the rhEGFR-Fc by the LAL method.

>95% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

See Certificate of Analysis for details of reconstitution instruction and specific concentration.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.

Please refer to product data sheet.

Clinical and Translational Updates

(1) "Guided neural regeneration with autologous fat grafting and oxygen hyperbaric therapy"
Toledo, Sangalette, Passerotti et al
Braz Oral Res (2021) 35, e138
(2) "Synthesis of Agarose-Based Multistimuli-Responsive Hydrogel Dressing for Accelerated Wound Healing"
Ying, Huang, Mao
ACS Biomater Sci Eng (2021)
(3) "Probing Indole Diketopiperazine-Based Hybrids as Environmental-Induced Products from Aspergillus sp. EGF 15-0-3"
Wei, Su, Hu et al
Org Lett (2021)
Showing 1-3 of 2983 papers.


(1) "Exploring the Antitumor Mechanisms of Zingiberis Rhizoma Combined with Coptidis Rhizoma Using a Network Pharmacology Approach"
Authors: Meng Wang, Youke Qi, Yongning Sun
Journal: BioMed Research International 2020
Application: SPR
(2) "Compositions and methods for treatment of cancer"
Authors: Lobb Roy, et al.
Journal: US20180142035A1 2018
Application: ELISA
(3) "Development of a protein nanoparticle platform for targeting EGFR expressing cancer cells"
Authors: Jakob W. Buecheler, et al.
Journal: J Chem Technol Bio 2014
Application: Biolayer interferometry (BLI)