Products

Biaffin

Newsletter

kinases protein kinase inhibitors signaling activators kinase substrates antibodies bioluminescence assays
Recombinant Human OX40 / TNFRSF4 / CD134 Protein, His-Tag, 100µg  

Recombinant Human OX40 / TNFRSF4 / CD134 Protein, His-Tag, 100µg

Recombinant Human OX40 / TNFRSF4 / CD134 Protein, His Tag (MALS verified) (rh TNFRSF4 / OX40 / CD134) Leu 29 - Ala 216 was produced in human 293 cells (HEK293) with a polyhistidine tag.

Synonym: recombinant, human, protein, TNFRSF4, OX40, CD134, OX40L receptor, ACT35, TXGP1L

More details

OX0-H5224-100

Availability: within 7 days

336,00 €

Background
Tumor necrosis factor receptor superfamily member 4 (TNFRSF4) is also known as ACT35 antigen, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, CD antigen CD134, OX40. OX40 / TNFRSF4 contains four TNFR-Cys repeats. TNFRSF4 is receptor for TNFSF4 / OX40L / GP34 and can interacts with TRAF2, TRAF3 and TRAF5.

Source
Recombinant Human OX40 Protein, His Tag (MALS verified) (OX0-H5224) is expressed from human 293 cells (HEK293). It contains AA Leu 29 - Ala 216 (Accession # P43489-1).
Predicted N-terminus: Leu 29

Molecular Characterization
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 22.0 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin
Less than 1.0 EU per μg of the rh TNFRSF4 / OX40 / CD134 by the LAL method.

Purity
>90% as determined by SDS-PAGE.

Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization.

Reconstitution
See Certificate of Analysis for details of reconstitution instruction and specific concentration.

Storage
Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at:
In lyophilized state for 1 year (4°C-8°C); After reconstitution under sterile conditions for 1 month (4°C-8°C) or 3 months (-20°C to -70°C).

Bioactivity
Please refer to product data sheet.

References

(1) Arch R.H., et al., 1998, Mol. Cell. Biol. 18:558-565.
(2) Kawamata S., et al., 1998, J. Biol. Chem. 273:5808-5814.

The following products could also be interesting for you: